Senolytics: Eradicating Zombie Cells to Extend Healthspan
The accumulation of senescent cells so called “zombie cells” that cease dividing but remain metabolically active has been identified as a fundamental driver of aging, comprising up to 15% of tissue volume in elderly individuals. These cells secrete a toxic mix of inflammatory cytokines known as the senescence associated secretory phenotype (SASP), which promotes tissue degeneration and systemic aging….