Category: Health & Beauty

The gut microbiome has emerged as a master regulator of aging, with fecal microbiota transplantation (FMT) from young donors demonstrating remarkable rejuvenating effects improving hippocampal neurogenesis by 40%, restoring thymic output, and reducing all cause mortality in progeroid mice by 60%. Mechanistic studies reveal that butyrate-producing bacteria like Faecalibacterium prausnitzii upregulate BDNF by 300%, while Bacteroides-derived bile…

The groundbreaking discovery that cellular aging can be reversed through epigenetic reprogramming has opened unprecedented possibilities for longevity science. By transiently expressing Yamanaka factors like OCT4, SOX2, KLF4, c-MYC, researchers can reset DNA methylation patterns to more youthful configurations without erasing cellular identity. The Salk Institute’s 2020 study demonstrated that intermittent OSKM expression extends lifespan…

The accumulation of senescent cells so called “zombie cells” that cease dividing but remain metabolically active has been identified as a fundamental driver of aging, comprising up to 15% of tissue volume in elderly individuals. These cells secrete a toxic mix of inflammatory cytokines known as the senescence associated secretory phenotype (SASP), which promotes tissue degeneration and systemic aging….

The decline of nicotinamide adenine dinucleotide (NAD+) with age represents one of the most compelling targets for anti-aging interventions. As an essential coenzyme in energy metabolism and DNA repair, NAD+ depletion reaching up to 50% reduction by age 60 directly contributes to mitochondrial dysfunction, epigenetic dysregulation, and impaired sirtuin activity. Recent breakthroughs have demonstrated that…